The design of drug safety packaging for the most p

2022-08-06
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Caring for vulnerable groups - children's drug safety packaging design

the World Health Organization lists accidental injury as the fifth cause of death of people worldwide. In China, the death caused by accidents accounts for about 50% of the total child mortality. In recent years, all localities have reported that the accidental death rate of primary and middle school students has reached 9.8/100 thousand and 75.36/100 thousand, accounting for 44.32% to 60.53% of the total death rate of primary and middle school students. Among them, the third largest killer of child accidents - child poisoning. The main reason is that children are naturally curious and good at imitating. They often like to explore this colorful world with taste

from the perspective of the whole society, strengthening children's awareness of safe packaging is the fundamental way to further reduce children's accidental ingestion of drugs. At the same time, strengthening the awareness of safe packaging is conducive to reflecting the state's attention to and protection of children's rights and interests, because it is a more humanized and scientific packaging method and concept that cares for vulnerable groups and pays more attention to social effects

in the survey results of Beijing drug market selected by the author, it is found that almost 95.5% of the drugs in the existing drug market do not have the function of children's drug packaging; In the samples sampled in the survey, the safety tips are generally only reflected in the simple text description, while in the safety design of the bottle mouth, only a very few health drugs (such as vitamins, shark essence, etc.) and children's cough medicine products have. The safety package of other blister packaged products is close to zero

this design will aim at the blank market and create a safety design for blister packaging drugs

1 performance requirements for blister drug packaging

(1) mechanical strength: impact strength, tensile strength, compression and rupture strength; (2) Isolation: moisture resistance, gas barrier, shading and fragrance retention; (3) Stability: light resistance, high temperature resistance, cold resistance, chemical corrosion resistance and aging resistance; (4) Safety and health: no harmful substances, toxic additives and impurities; (5) Non reactivity: no reaction or absorption with the internal agent; (6) Operability: suitable for packaging equipment processing; (7) Merchantability: transparency and gloss; (8) Easy to discard: reduced volume, good environmental protection; (9) Economic benefit: production efficiency, low cost of packaging base material. Some pharmaceuticals need a shelf life of 5 years, especially for drugs that absorb moisture and are prone to oxidation and deterioration, the packaging is required to be highly barrier. Within the 5-year storage period of drug packaging, if the oxygen barrier change is greater than 0-1mml/m2, the packaged drugs will have problems. If it is less than this value, it generally meets the requirements of drugs; For example, the barrier requirement within 5 years of packaging is more stringent than the variation range of 0-1mml/m2, so a substrate with high barrier is required, such as aluminum foil

2 design basis of children's safety packaging

safe drug packaging to prevent children from opening European and American countries attach great importance to this issue. They noticed this issue in the 1970s. In 1974, the legislation strongly attracted more and more attention. All oral drugs adopt safe packaging to prevent children from opening, which has been implemented for 20 years. However, for Chinese Mainland, the safety packaging to prevent children from opening is relatively rare in the market. In addition to complying with certain requirements for drug safety packaging, the packaging design shall also consider:

1) ergonomics. Because the strength of children's hands is much weaker than that of adults, and children are still developing the coordination ability of limb activities, they are unable to perform some more complex actions, such as turning after pressing down or lifting up after pressing down

2) visual warning angle. Packaging labels of different colors can be used to indicate danger and improve attention, and some warning tones can be used to divert children's interest. At the same time, they can be found by the guardian and stopped in time. The research report points out that black and red images have the most significant effect on indicating danger, while red and green images are more effective in improving attention

3) from the perspective of child behavioral psychology and ethology. Children have strong curiosity and imitation ability. They like to experience the colorful world through taste. In their eyes, all the untouched things are fresh. This intense quest for knowledge impels them to try these so-called things according to the behavior of adults. Something new. At the same time, children generally have a one-time behavior when they touch something, that is, when they fail to open the object for the first time, they generally give up on their own initiative, so as to transfer the target and capture another new thing. Taking advantage of this one-time behavior of children gives great enlightenment to children's safety packaging: we can design a relatively simple way to open items after more than two times, so as to effectively prevent children from eating by mistake

3 safety blister packaging design scheme I

blister packaging is a kind of hot pressing packaging method with controllable dose. It is very convenient for users to take out the packaged articles by simple extrusion. At present, blister packaging has been widely used in pharmaceutical packaging to gradually replace the bottled method. It has good protection performance; Convenient medication; Fast production speed; Low cost; Convenient transportation; Small storage space

this design follows the design basis of children's safety packaging. By connecting the two blisters together, the purpose of successful drug taking can be achieved only after two actions. This design idea is mainly to grasp the characteristics of one behavior action of infants and children, and achieve drug taking through two actions, which relatively causes a certain degree of artificial obstacles to children. However, for adults, it does not affect the drug taking action, the standard system and results of full coverage of production process and detection methods

3.1 scheme content

1) a blister B (plastic hard sheet) with supporting plate, which is mainly made of PVC; The supporting plate is mainly made of PTP aluminum foil. The blister is provided with medicine

2) a blister a without supporting plate, which is mainly made of PVC. And there is a closed weakening line type tear wire along the blister plate. Pull the pull wire to ensure that the pulling action is realized, and take out the medicine twice

3.2 action implementation process

since the blister without plate and the blister with plate are connected together, when the user pushes the blister plate B with force, the drug is extruded smoothly through the aluminum foil and directly falls into the blister plate a, and then the user takes out the drug through the tear wire on the blister plate a to realize the second action. This design effectively delays the time of one action of children due to curiosity, thus relatively improving the safety of drug packaging

3.3 design advantages

grasp the behavior characteristics of children in one action, and design a tear and pull drug taking method to cause relatively artificial obstacles to children. At the same time, the tear type weakening line is designed on the blister like structure a, while the drug filling position is in the blister B, which effectively ensures the moisture-proof and anti-oxidation problems in the drug packaging. That is, blister B not only plays the role of setting obstacles, but also ensures the drug performance requirements

4 safety blister packaging design scheme II

4.1 scheme content

this scheme design is inspired by music greeting cards and is conceived based on the effect of music or warning lights on children. Its principle and process are relatively simple. It is mainly to connect the two blister plates and place the sound control switch at the joint. The user can start the switch when opening the blister connector and close the switch when closing the connector. The sounder is mainly composed of wires, button batteries, springs, tributary sounders and light-emitting diodes

4.2 after the action is implemented

open the blister connector, the power supply starts to emit music diode light; Close the blister connector, and the power supply closing task ends

4.3 design you1dan insurance company hopes to have the effect point of yu'e Bao version Monetary Fund

utilization {with the bubble cap packaging of music greeting cards, the joint of two independent bubble cap packaging can be opened. At the same time, the pleasant music and flashing light will attract children trying to take medicine. This wait 3. The measurement of beam displacement is about the same as the measurement of deformation. The time and sound just attract the attention of parents or guardians to effectively avoid accidents.

5 conclusion

in China's increasingly mature packaging market, enterprises as market cells should Gradually realize that only enterprises with a certain society can better obtain competitive advantage. Let's care for vulnerable groups and design safer drug packaging for them

Zhu Hui1, huangzhigang 2, zhangyudong 3

1. Beijing University of technology 2. Beijing Industrial and Commercial University; 3. Law Press

reprinted from: Packaging Engineering

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